Feb 8, 2025, 5:50 PM
Feb 7, 2025, 1:00 PM

New Hampshire man undergoes successful pig kidney transplant

Highlights
  • Andrews was the second recipient of a genetically edited pig kidney at Massachusetts General Hospital, following a previous similar transplant that resulted in the patient's death due to unrelated health issues.
  • His health had been deteriorating while on dialysis, prompting him to volunteer for this pioneering transplant study.
  • The successful operation offers hope for those in need of organ transplants as the medical community explores alternatives to human organ donation.
Story

In the United States, specifically at Massachusetts General Hospital, a significant medical event took place on January 25, 2025, when a New Hampshire man named Andrews underwent a successful transplant of a genetically engineered pig kidney. This operation is part of an effort to address the severe organ shortage affecting many Americans, particularly those in need of kidney transplants. The medical team, led by Dr. Tatsuo Kawai, successfully facilitated this pioneering procedure as Andrews had been struggling with the negative effects of dialysis due to worsening health conditions. As the first person who previously received a pig kidney transplant died within two months after the surgery, doctors were cautious but hopeful regarding Andrews' procedure. The news was carefully monitored, especially since Andrews had a history of diabetic complications, which further complicated his health. However, thorough examinations indicated that his heart was in excellent condition, making him a suitable candidate for this xenotransplant pilot study. Following the transplant, Andrews experienced immediate positive outcomes, as his new kidney began functioning soon after the surgery, notably producing urine within ten minutes. This early success has energized both Andrews and the medical staff, who hope that these kinds of procedures can lead to improved kidney transplant survival rates and application for more patients on the transplant waiting list. The implications of this study are significant, as there are over 100,000 individuals in the U.S. waiting for organ transplants, the majority requiring kidneys. If this pilot study progresses favorably, larger clinical trials may follow, potentially benefiting many more patients who are currently dependent on dialysis. Andrews expressed his desire to share his experience and the hope he has found through this unprecedented medical intervention with others still facing kidney challenges.

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