West Nile virus spreads across US and Europe without a cure

West Nile virus, a mosquito-borne disease, has been spreading across the US and Europe for decades, with over 59,000 reported cases and more than 2,900 deaths in the US alone. The virus can lead to severe neurological complications, including brain inflammation and damage, affecting approximately 1 in 150 infected individuals. Despite its prevalence, there is currently no vaccine or dedicated treatment available for those infected, highlighting the disease's neglected status. Experts like Kristy Murray emphasize the urgent need for effective treatments, particularly drugs that can reduce inflammation in the brain. The lack of financial incentives for pharmaceutical companies has hindered vaccine development, with previous trials failing to progress beyond initial phases. Climate change is raising concerns about the increasing frequency of outbreaks, necessitating a coordinated international response to gather evidence and develop effective interventions. Proposals for large-scale trials in endemic regions, including parts of Africa, have been suggested as a way to address the urgent need for a vaccine and treatment options. The potential for using steroids to manage inflammation in severe cases is being explored, with experts believing that sufficient funding and political will could lead to significant advancements in combating this neglected disease.