Jonas Brothers release uplifting song 'I Can't Lose' for cancer support

On July 16, 2025, the Jonas Brothers, consisting of Joe Jonas, Kevin Jonas, and Nick Jonas, returned to the music scene with their latest single, 'I Can't Lose.' This release, which also included an accompanying music video, is aimed at supporting Stand Up to Cancer in partnership with Mastercard. The song was designed to evoke themes of love and resilience, serving as a reminder for listeners to show up for the people they care about. The band expressed their hope that the track would resonate with a diverse audience, allowing it to carry different meanings based on individual experiences. 'Greetings From Your Hometown,' the upcoming album that features this song, is set to be released on August 8, 2025. Alongside 'I Can't Lose,' the album will include previously released tracks such as 'Love Me to Heaven,' 'No Time to Talk,' and 'Slow Motion.' This illustrates the Jonas Brothers' continued commitment to creating meaningful music while also addressing important issues through their art. The music video showcases a live rooftop performance where the band engages with fans, further emphasizing the communal aspect of the song's message. The Jonas Brothers have a significant history of creating music that connects with fans, and 'I Can't Lose' continues that tradition. The decision to partner with Stand Up to Cancer and Mastercard highlights their desire to use their platform for positive impact, raising awareness and encouraging support for those affected by cancer. The band has noted their intention for the song to serve as a reminder of the strength within individuals during challenging times. This project reflects their artistic growth and evolving focus on more profound societal themes, which has garnered considerable anticipation from their fanbase. With 'I Can't Lose,' the Jonas Brothers not only deliver a song that is poised to be an anthem for empowerment but also ensure that their work contributes to meaningful causes. Their efforts to support cancer awareness resonate widely, and the upcoming album promises to be a significant addition to their discography, appealing to both longtime fans and new listeners who appreciate music with heart and purpose.