Kidney disease deaths surged by 24% over three decades

In March 2025, significant concerns were raised regarding the global rise in chronic kidney disease, with reports indicating that the rate of death from this condition had increased 24% from 1990 to 2021. This alarming statistic was published by the American Heart Association, emphasizing the critical connection between kidney health and cardiovascular health. Despite kidney disease being a powerful risk predictor for heart conditions, it is concerning that approximately 9 in 10 U.S. adults suffering from chronic kidney disease are unaware of their condition, which complicates early intervention efforts. The interplay between kidney health and cardiovascular disease is characterized by an area of medical study known as the cardio-kidney domain. Experts noted that the co-occurrence of cardiovascular and kidney issues is often described as the cardiovascular-kidney-metabolic (CKM) syndrome, a situation where interconnected conditions such as obesity, hypertension, and diabetes increase health risks. Treating kidney issues is viewed as a potential pathway to reduce the morbidity and mortality associated with cardiovascular diseases, which include heart disease, heart failure, and stroke. The findings underline the pressing need for comprehensive screenings and integrated care models that address both kidney and heart health, as well as promote metabolic health. With excess body weight being linked to lower levels of kidney health, controlling risks associated with weight, blood pressure, lipids, and blood glucose can greatly improve patients' cardiovascular outcomes and overall health. Authorities are advocating for interdisciplinary care strategies to raise awareness among healthcare providers and patients alike concerning the significance of kidney health. As a result of the CKM Health Initiative, supported by various healthcare organizations, efforts are underway to promote better screening and treatment options for individuals living with CKM syndrome. These initiatives aim to enhance quality of life and improve health outcomes by identifying risks earlier and implementing evidence-based practices that integrate cardiovascular and kidney care. The American Heart Association underscores the importance of comprehensively understanding and addressing the connections between these critical health domains to combat this growing health crisis effectively.