Millions suffer from side effects of blood pressure medications in the UK

In the UK, millions are taking blood pressure medications, ramipril and amlodipine, which can cause side effects like a dry cough and swollen ankles. NHS GP Dr Amir Khan has warned that many patients may misinterpret these symptoms as unrelated health issues. He advises that individuals experiencing these side effects should consult their healthcare providers to address their concerns and ensure proper management of their blood pressure medications.

Millions suffer from side effects of blood pressure medications in the UK
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science Published Aug 7, 2026

Topic overview

In brief

  • Millions of Britons are taking blood pressure medications like ramipril and amlodipine.
  • Common side effects include a dry cough and swollen ankles, which may lead patients to stop taking their medications.
  • Patients experiencing these symptoms should consult a healthcare professional for advice.

Summary

In the UK, millions of individuals are currently taking blood pressure medications, specifically ramipril and amlodipine, which have been linked to several concerning side effects. NHS GP and ITV medic Dr Amir Khan has raised awareness about these potential issues, particularly a painful, dry cough that many patients may mistakenly attribute to a chest infection. This cough is a result of ramipril triggering the release of bradykinin, a substance that irritates the airways. Additionally, amlodipine can lead to fluid leakage into the ankles, causing swelling, a condition known as oedema.

Dr Khan emphasized that many patients might be suffering in silence or even discontinuing their medications due to these side effects. He noted that around one in 100 individuals taking ramipril experience common symptoms alongside the dry cough. More severe side effects can also occur, such as yellowing of the eyes or skin, which may indicate liver issues, and symptoms like feeling faint or dizzy, which could signal more serious health concerns.

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Updated Aug 7, 2026

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